I like to mix and match..
For example I like the general look of LB Photo, but the signs are hard to read and the font is terrible.. however "Misa's" has an ideal font package..
So, I copy the "font" folder out of misa's and put it in LB Photo.. now chat is smaller and is actually readable.. especially with the new chat updates in 1.2.4
Same with signs.. they are too dark.. So I lighten up the sign texture with good ol' picture editor, now you can read them from across the way.
You can also lighten up the GUI, especially the inventory gui to make it easier to see your items, like the ever hidden single stick..